ConditionandTreatments

Overview

Assisted hatching is a laboratory technique used in in vitro fertilization (IVF) to improve the chances of embryo implantation. During the early stages of embryo development, the embryo is surrounded by a protective shell called the zona pellucida. For successful implantation in the uterus, the embryo must "hatch" out of this shell. In some cases, especially in older women or those with previous failed IVF attempts, the zona pellucida may be thicker or harder, making it difficult for the embryo to hatch naturally. Assisted hatching involves creating a small opening in the zona pellucida to facilitate hatching and increase the likelihood of implantation.

Recommendations

Patients who may be recommended for assisted hatching often have certain characteristics, such as:

• Advanced maternal age.
• History of failed IVF cycles.
• Poor embryo quality.
• Thickened zona pellucida observed in previous IVF cycles.

Types of Assisted Hatching

There are several methods of assisted hatching, including:

Mechanical Hatching

A fine needle or pipette is used to mechanically create a small hole in the zona pellucida.

Chemical Hatching

A mild acidic solution is applied to thin the zona pellucida or create a small opening.

Laser-Assisted Hatching

A laser is used to precisely create an opening in the zona pellucida. This method is the most commonly used due to its precision and safety.

Diagnosis

Assisted hatching is not a diagnostic procedure, but it may be recommended based on certain factors observed during the IVF process. These factors include:

• A history of multiple unsuccessful IVF attempts.
• The observation of a thick or hard zona pellucida in previous IVF cycles.
• The age of the female partner, particularly if she is 37 years or older.

Treatment

The assisted hatching procedure is performed on embryos in the laboratory before they are transferred to the uterus. The steps involved include:

Preparation of the Embryo

The embryo is carefully assessed under a microscope, and the zona pellucida is evaluated.

Hatching Procedure

Depending on the method chosen (mechanical, chemical, or laser), a small opening is made in the zona pellucida.

Embryo Transfer

After assisted hatching, the embryo is cultured for a short period before being transferred into the uterus for implantation.

Meditation and Surgery

Meditation is not directly related to the assisted hatching procedure. However, patients undergoing IVF may benefit from meditation or other relaxation techniques to reduce stress and anxiety associated with fertility treatments. Surgery is not involved in the assisted hatching process, as it is a non-invasive laboratory technique performed on embryos outside the body.

FAQ

• Is assisted hatching painful?

  No, assisted hatching is performed on embryos in a laboratory setting and does not cause any pain to the patient.

• Who is a candidate for assisted hatching?

  Candidates include women over the age of 37, those with a history of failed IVF cycles, or those with embryos that have a thick zona pellucida.

• Does assisted hatching guarantee pregnancy?

  While assisted hatching can improve the chances of implantation, it does not guarantee pregnancy. Success depends on various factors, including the overall quality of the embryos.

• Are there any risks associated with assisted hatching?

  The procedure is generally safe, but there is a small risk of damage to the embryo or incorrect hatching.

• How do I know if I need assisted hatching?

  Your fertility specialist will assess your individual case and may recommend assisted hatching if they believe it will increase your chances of a successful pregnancy.